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About Us

ACI Children's Center for Diabetes and Cancer Research

305 Madison Ave
Lincoln Building,
Science Center 449,
New York, NY 10165

Research in the Field

Our Center focuses on providing grant funding for scientists working on cures in the fields of Diabetes and Cancer. Diabetes is a serious and costly disease which is becoming increasingly common, especially in developing countries and disadvantaged minorities. It is a leading cause of death by disease. It can lead to heart attack, stroke, kidney disease, amputation and blindness.
(Diabetes mellitus is a chronic disease caused by inherited and/or acquired deficiency in production of insulin by the pancreas, or by the ineffectiveness of the insulin produced. Such a deficiency results in increased concentrations of glucose in the blood, which in turn damage many of the body's systems, in particular the blood vessels and nerves.) The scale of the problem that diabetes poses to world health is still widely under recognized. At least 177 million people worldwide suffer from diabetes; this figure is likely to more than double by 2025. Diabetic retinopathy is a leading cause of blindness and visual disability. - (Diabetes mellitus is associated with damage to the small blood vessels in the retina, resulting in loss of vision.) - Findings, consistent from study to study, make it possible to suggest that, after 15 years of diabetes, approximately 2% of people become blind, while about 10% develop severe visual handicap. Diabetes is among the leading causes of kidney failure, but its frequency varies between populations and is also related to the severity and duration of the disease. Heart disease accounts for approximately 50% of all deaths among people with diabetes in industrialized countries. Diabetes negates the protection from heart disease which pre-menopausal women without diabetes experience. Diabetic neuropathy - (Neuropathy can lead to sensory loss and damage to the limbs and is also a major cause of impotence in diabetic men) - is probably the most common complication of diabetes - up to 50% of people with diabetes are affected to some degree. Diabetic foot disease often leads to ulceration and subsequent limb amputation. It is one of the most costly complications of diabetes. Diabetes is the most common cause of non-traumatic amputation of the lower limb.

Cancer is the uncontrolled growth and spread of cells that may affect almost any tissue of the body. Lung, colorectal and stomach cancer are among the five most common cancers in the world for both men and women. Among men, lung and stomach cancer are the most common cancers worldwide. For women, the most common cancers are breast and cervical cancer. More than 10 million people are diagnosed with cancer every year. It is estimated that there will be 15 million new cases every year by 2020.

Cancer causes 6 million deaths every year—or 12% of deaths worldwide. There are around 200 different types of cancer. Some are very common, while others are extremely rare - some types of blood cancer make up less than 1 in 100 new cases.

In the United States, approximately 8,600 children were diagnosed with cancer and about 1,500 children died from the disease in 2001. This makes cancer the leading cause of death by disease among U.S. children under age 15. Among the 12 major types of childhood cancers, leukemias (blood cell cancers) and brain and other central nervous system tumors account for over one-half of the new cases. About one-third of childhood cancers are leukemias; approximately 2,700 children (younger than 15 years) were diagnosed with leukemia in 2001. The most common type of leukemia in children is acute lymphocytic leukemia. The most common solid tumors are brain tumors (e.g., gliomas and medulloblastomas), with other solid tumors (e.g., neuroblastomas, Wilms’ tumors, and rhabdomyosarcomas) being less common.